RACGAP1 抗体
Our Local Distributor
北京 101111
Quick Overview for RACGAP1 抗体 (ABIN498154)
抗原
See all RACGAP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- This antibody detects endogenous levels of MgcRacGAP protein.
-
交叉反应 (详细)
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen
-
纯度
- > 95 % (by SDS-PAGE)
-
-
-
-
应用备注
-
Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))
-
别名
- RACGAP1
-
背景
- Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.Synonyms: KIAA1478, MGCRACGAP, Male germ cell RacGap, Rac GTPase-activating protein 1
-
分子量
- approx. 72 kDa
-
基因ID
- 29127
-
NCBI登录号
- NP_001119575
-
UniProt
- Q9H0H5
-
途径
- Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor
抗原
-