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HNRNPD/AUF1 抗体

The 兔 多克隆 anti-HNRNPD/AUF1 antibody (ABIN498144) specifically detects HNRNPD/AUF1 in WB, IF 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN498144
发货至: 中国
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Quick Overview for HNRNPD/AUF1 抗体 (ABIN498144)

抗原

See all HNRNPD/AUF1 (HNRNPD) 抗体
HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))

适用

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人, 小鼠, 大鼠

宿主

  • 65
  • 6

克隆类型

  • 66
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多克隆

标记

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This HNRNPD/AUF1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of hnRPD protein.

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse, Rat.

    纯化方法

    Affinity-chromatography using epitope-specific immunogen
  • 应用备注

    Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate Buffered Saline (PBS), pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))

    别名

    HnRNP-D0 / HNRNPD

    背景

    HnRNP D/AUF1 binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3' untranslated regions of many protooncogenes and cytokine mRNAs. It also binds to double and single stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single stranded nonmonotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. It may be involved in translationally coupled mRNA turnover (referenced from swissprot).Synonyms: AU-rich element RNA-binding protein 1, AUF1, HNRPD, Heterogeneous nuclear ribonucleoprotein D0

    分子量

    approx. 38 kDa

    基因ID

    3184

    NCBI登录号

    NP_001003810

    UniProt

    Q14103
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