HDAC6 抗体
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北京 101111
Quick Overview for HDAC6 抗体 (ABIN498134)
抗原
See all HDAC6 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of HDAC6 protein.
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交叉反应 （详细）
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Histone Deacetylase 6 (HDAC6) (AA 560-811) antibody
HDAC6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 6 (HDAC6) antibodyHDAC6 适用: 人, 大鼠, 猴, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 4C5 unconjugated
anti-Histone Deacetylase 6 (HDAC6) antibodyHDAC6 适用: 人, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Histone Deacetylase 6 (HDAC6) (AA 1-200) antibodyHDAC6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 6 (HDAC6) (AA 166-348) antibodyHDAC6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 6 (HDAC6) (AA 1128-1215) antibodyHDAC6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E2 unconjugated
anti-Histone Deacetylase 6 (HDAC6) antibodyKD Validated HDAC6 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB6170 unconjugated Recombinant Antibody
anti-Histone Deacetylase 6 (HDAC6) antibodyHDAC6 适用: 人 WB, ELISA, IP, ICC, ICFC 宿主: 小鼠 Monoclonal 236 unconjugated
anti-Histone Deacetylase 6 (HDAC6) (C-Term) antibodyVerified HDAC6 适用: 人 IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Histone Deacetylase 6 (HDAC6) (AA 69-118) antibodyHDAC6 适用: 人, 小鼠, 猴, 兔, 马, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- HDAC6 (Histone Deacetylase 6 (HDAC6))
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别名
- HDAC6
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背景
- HDAC6 is a member of the class II mammalian histone deacetylases. Human HDAC6 is composed of 1215 amino acid residues. It possesses two separate putative catalytic domains. Both catalytic domains are fully functional HDACs and contribute independently to the overall activity of HDAC6 protein. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. The expression of HDAC6 is tightly linked to the state of cell differentiation. HDAC6 may participate in coordinating expression of a group of genes involved in the remodelling of chromatin during cell differentiation.Synonyms: HD6, Histone deacetylase 6, JM21, KIAA0901
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分子量
- approx. 131 kDa
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基因ID
- 10013
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NCBI登录号
- NP_006035
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UniProt
- Q9UBN7
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
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