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GATA4 抗体

The 兔 多克隆 anti-GATA4 antibody (ABIN498129) specifically detects GATA4 in WB 和 IF. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN498129
发货至: 中国
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Quick Overview for GATA4 抗体 (ABIN498129)

抗原

See all GATA4 抗体
GATA4 (GATA Binding Protein 4 (GATA4))

适用

  • 94
  • 68
  • 66
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 86
  • 10
  • 1

克隆类型

  • 67
  • 30
多克隆

标记

  • 61
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GATA4 antibody is un-conjugated

应用范围

  • 78
  • 33
  • 32
  • 19
  • 16
  • 13
  • 13
  • 13
  • 10
  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • 特异性

    This antibody detects endogenous levels of GATA4 protein.

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography using epitope-specific immunogen

    纯度

    > 95 % (by SDS-PAGE)
  • 应用备注

    Western blot: 1: 500 - 1: 1000. Immunoflourescence: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    GATA4 (GATA Binding Protein 4 (GATA4))

    别名

    GATA4

    背景

    GATA4 is a 46 kDa member of the GATA family of zinc finger containing transcription factors that is involved in the development of cardiac hypertrophy and remodeling, and plays a critical role in regulating basal and agonist or stress induced gene expression in cardiac and smooth muscle cell types. GATA4 contains a conserved MAPK phosphorylation site at serine 105 within the transcriptional activation domain. Serine 105 of GATA4 is phosphorylated in response to agonist stimulation through MEK 1 ERK1 / 2, and weakly through JNK or p38 MAPKs.Synonyms: GATA-4, GATA-binding factor 4, Transcription factor GATA-4

    分子量

    approx. 48 kDa

    基因ID

    2626

    NCBI登录号

    NP_002043

    UniProt

    P43694

    途径

    Peptide Hormone Metabolism, Carbohydrate Homeostasis
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