Aurora A 抗体
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北京 101111
Quick Overview for Aurora A 抗体 (ABIN498104)
抗原
See all Aurora A (AURKA) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody antibody detects endogenous levels of of AurA protein.
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Aurora Kinase A (AURKA) (AA 1-110) antibody
AURKA 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5F8 unconjugated
anti-Aurora Kinase A (AURKA) (AA 268-404) antibodyAURKA 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 2D8A4 unconjugated
anti-Aurora Kinase A (AURKA) (C-Term) antibodyAURKA 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aurora Kinase A (AURKA) (AA 364-392), (C-Term) antibodyAURKA 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB6834 unconjugated
anti-Aurora Kinase A (AURKA) antibodyAURKA 适用: 人, 大鼠, 猴 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1F8 unconjugated
anti-Aurora Kinase A (AURKA) (pThr288) antibodyAURKA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aurora Kinase A (AURKA) antibodyAURKA 适用: 人, 大鼠, 猴 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 4G10 unconjugated
anti-Aurora Kinase A (AURKA) (AA 268-404) antibodyAURKA 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 4H5A8 unconjugated
anti-Aurora Kinase A (AURKA) (AA 364-392) antibodyAURKA 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Aurora Kinase A (AURKA) (AA 1-131) antibodyAURKA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blots: 1/500approx. 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Aurora A (AURKA) (Aurora Kinase A (AURKA))
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别名
- Aurora Kinase A
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背景
- Aurora 2/AIK, a cell cycle-regulated serine/threonine protein kinase, is overexpressed in many tumor cell lines. Phosphorylation of threonine 288, which is within the activation loop of the kinase, results in a significant increase in its enzymatic activity. Aurora 2/AIK is regulated by proteasome-dependent degradation, and phosphorylation on Thr288 may target it for degradation during mitosis. Thus, phosphorylation of Aurora 2/AIK at Thr288 is important for both kinase activity and stability.Synonyms: AIK1, ARK1, AURA, AURKA, AURORA2, Aurora/IPL1-related kinase 1, BTAK, Breast tumor-amplified kinase, STK15, STK6, Serine/threonine kinase 15, Serine/threonine-protein kinase 6
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分子量
- approx. 48 kDa
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基因ID
- 6790
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NCBI登录号
- NP_003591
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UniProt
- O14965
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途径
- Cell Division Cycle, Asymmetric Protein Localization
抗原
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