ATG16L1 抗体 (N-Term)
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Quick Overview for ATG16L1 抗体 (N-Term) (ABIN497988)
抗原
See all ATG16L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- Recognizes ATG16 (N-term).
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse and Rat.
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- ATG16 antibody was raised against a 18 amino acid peptide from near the amino terminus of Human ATG16 (Genbank accession No. NP_110430).
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亚型
- IgG
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anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 200-300) antibody
ATG16L1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 342-607) antibodyATG16L1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 1-284) antibodyATG16L1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 11-257) antibodyATG16L1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5H9A11 unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 161-190) antibodyATG16L1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB07490 unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 84-114) antibodyATG16L1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 501-607) antibodyATG16L1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 90-300) antibodyATG16L1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 11-257) antibodyATG16L1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8F8C2 unconjugated
anti-ATG16 Autophagy Related 16-Like 1 (ATG16L1) (AA 90-300) antibodyATG16L1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: ATG16 antibody can be used for the detection of ATG16 at 0.5-1 μg/mL. Immunocytochemistry. Positive Control: HeLa Cell Lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))
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别名
- APG16L / ATG16L1
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背景
- Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG16, another member of the autophagy protein family, forms a complex with the ATG5-ATG12 conjugate. This multimeric protein has been shown to be essential for autophagosome formation in both yeast and mammals and targets the ATG5-ATG12 complex to the autophagic isolation membrane during the formation of the autophagosome. Because mammalian ATG16 has seven WD-repeats in its C-terminal domain, it has been suggested that these may form a platform for further protein-protein interactions. Multiple isoforms of ATG16 are known to exist.Synonyms: APG16-like 1, Autophagy-related protein 16-1
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基因ID
- 55054
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NCBI登录号
- NP_110430
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UniProt
- Q676U5
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途径
- Autophagy
抗原
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