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ATG10 抗体 (C-Term)

This anti-ATG10 antibody is a 兔 多克隆 antibody detecting ATG10 in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN497986
发货至: 中国

Quick Overview for ATG10 抗体 (C-Term) (ABIN497986)

抗原

See all ATG10 抗体
ATG10 (Autophagy Related 10 (ATG10))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ATG10 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    Recognizes APG10L/ATG10 (C-term).

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse and Rat

    纯化方法

    Immunoaffinity Chromatography

    免疫原

    ATG10 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of Human ATG10 (Genbank accession No. EAW95884).

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: ATG10 antibody can be used for the detection of ATG10 at 0.5-1 μg/mL. Positive Control: SK-N-SH Cell Lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    ATG10 (Autophagy Related 10 (ATG10))

    别名

    APG10L / ATG10

    背景

    Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. Another member of the autophagy protein family is ATG10, an E2-like enzyme involved in two ubiquitin-like modifications essential for autophagosome formation: ATG12-ATG5 conjugation and the modification of a soluble form of MAP-LC3, a homolog of yeast Apg8, to a membrane-bound form. ATG10 has also been shown to interact with ATG12 in human embryonic kidney cells in the presence of ATG7. Multiple isoforms of ATG10 are known to exist.Synonyms: Autophagy-related protein 10

    基因ID

    83734

    NCBI登录号

    NP_001124500

    UniProt

    Q9H0Y0

    途径

    ER-Nucleus Signaling, Autophagy
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