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ATG12 抗体 (Middle Region)

ATG12 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN497964
发货至: 中国
  • 抗原 See all ATG12 抗体
    ATG12 (Autophagy Related 12 (ATG12))
    抗原表位
    • 19
    • 15
    • 8
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 84
    • 36
    • 25
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 76
    • 23
    • 3
    • 1
    克隆类型
    • 77
    • 26
    多克隆
    标记
    • 47
    • 8
    • 8
    • 8
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATG12 antibody is un-conjugated
    应用范围
    • 82
    • 49
    • 39
    • 30
    • 22
    • 13
    • 13
    • 11
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    Recognizes APG12/ATG12.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse and Rat
    纯化方法
    Affinity Chromatography purified via peptide column
    免疫原
    A 15 amino acid peptide from near the center of Human ATG12
    亚型
    IgG
    Top Product
    Discover our top product ATG12 Primary Antibody
  • 应用备注
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    ATG12 (Autophagy Related 12 (ATG12))
    别名
    ATG12 / APG12 (ATG12 产品)
    别名
    APG12 antibody, APG12L antibody, FBR93 antibody, HAPG12 antibody, Apg12l antibody, AUTOPHAGY 12 antibody, AUTOPHAGY 12 B antibody, CG10861 antibody, Dmel\\CG10861 antibody, atg12 antibody, ATG12 antibody, apg12 antibody, DDBDRAFT_0185323 antibody, DDBDRAFT_0191412 antibody, DDB_0185323 antibody, DDB_0191412 antibody, 4931423H11Rik antibody, A330058M13Rik antibody, Atg12l antibody, AO090001000593 antibody, autophagy related 12 antibody, Ubiquitin-like superfamily protein antibody, Atg12p antibody, autophagy protein antibody, ubiquitin-like protein ATG12B antibody, autophagy associated protein Atg12 antibody, Autophagy-related 12 antibody, ATG12 autophagy related 12 homolog (S. cerevisiae) antibody, ATG12 autophagy related 12 homolog (S. cerevisiae) pseudogene antibody, autophagy associated ubiquitin-like modifier Atg12 antibody, hypothetical protein antibody, Autophagy-related protein 12 (Autophagy-related ubiquitin-like modifier ATG12) antibody, autophagy protein 12 antibody, autophagy related 12 S homeolog antibody, autophagy-related protein 12 antibody, ATG12 antibody, Atg12 antibody, APG12B antibody, APG12 antibody, LOC9321066 antibody, apg12 antibody, atg12 antibody, LOC743425 antibody, CAALFM_C113950CA antibody, atg12.S antibody, ANI_1_922094 antibody, AOR_1_1064164 antibody
    背景
    Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG12, another member of the autophagy protein family, forms a conjugate with ATG5, this conjugate has a ubiquitin-protein ligase (E3)-like activity for protein lipidation in autophagy. This conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as IPS-1), inhibiting type I interferon production and permitting viral replication in host cells. ATG12 has also been shown to interact with ATG10 in human embryonic kidney cells in the presence of ATG7. At least two isoforms of ATG12 are known to exist.Synonyms: APG12-like, APG12L, Autophagy-related protein 12, Ubiquitin-like protein ATG12
    基因ID
    9140
    NCBI登录号
    NP_004698
    UniProt
    O94817
    途径
    Autophagy
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