Cadherin 5 抗体 (AA 106-134)
Quick Overview for Cadherin 5 抗体 (AA 106-134) (ABIN3030247)
抗原
See all Cadherin 5 (CDH5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 106-134
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 106-134 from the human protein was used as the immunogen for this VE Cadherin antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the VE Cadherin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the VE Cadherin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Cadherin 5 (CDH5)
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别名
- VE Cadherin (CDH5)
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背景
- CDH5 is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.
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UniProt
- P33151
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途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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