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Vitamin D Receptor 抗体 (AA 274-299)

This anti-Vitamin D Receptor antibody is a 兔 多克隆 antibody detecting Vitamin D Receptor in WB, ELISA 和 FACS. Suitable for 人.
产品编号 ABIN3029599
发货至: 中国

Quick Overview for Vitamin D Receptor 抗体 (AA 274-299) (ABIN3029599)

抗原

See all Vitamin D Receptor (VDR) 抗体
Vitamin D Receptor (VDR)

适用

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宿主

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克隆类型

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多克隆

标记

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This Vitamin D Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 274-299

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 274-299 from the human protein was used as the immunogen for this VDR antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the VDR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the VDR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Vitamin D Receptor (VDR)

    别名

    VDR

    物质类

    Chemical

    背景

    This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein.

    UniProt

    P11473

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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