NKX2-1 抗体 (AA 2-1)
Our Local Distributor
北京 101111
Quick Overview for NKX2-1 抗体 (AA 2-1) (ABIN3029203)
抗原
See all NKX2-1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 2-1
-
交叉反应 (详细)
- Expected species reactivity: Mouse, Rat
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 2-1 from the human protein was used as the immunogen for this TTF1 antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the TTF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the TTF1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- NKX2-1 (NK2 Homeobox 1 (NKX2-1))
-
别名
- NKX2.1 (TTF1)
-
背景
- This gene encodes a protein initially identified as a thyroid-specific transcription factor. NKX2.1/TTF1 binds to thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
-
UniProt
- P43699
-
途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
抗原
-