PLAT 抗体 (AA 371-399)
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北京 101111
Quick Overview for PLAT 抗体 (AA 371-399) (ABIN3032243)
抗原
See all PLAT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 371-399
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纯化方法
- Purified
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免疫原
- A portion of amino acids 371-399 from the human protein was used as the immunogen for this tPA antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the tPA antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the tPA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PLAT (Plasminogen Activator, Tissue (PLAT))
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别名
- TPA
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背景
- TPA is a tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism.
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UniProt
- P00750
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途径
- Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome
抗原
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