TLR7 抗体 (AA 899-926)
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Quick Overview for TLR7 抗体 (AA 899-926) (ABIN3029177)
抗原
See all TLR7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 899-926
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交叉反应 (详细)
- Expected species reactivity: Mouse
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 899-926 from the human protein was used as the immunogen for this TLR7 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the TLR7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the TLR7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- TLR7 (Toll-Like Receptor 7 (TLR7))
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别名
- TLR7
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背景
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.
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UniProt
- Q9NYK1
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途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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