TLR6 抗体 (AA 1-30)
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北京 101111
Quick Overview for TLR6 抗体 (AA 1-30) (ABIN3029175)
抗原
See all TLR6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-30
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纯化方法
- Purified
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免疫原
- A portion of amino acids 1-30 from the mouse protein was used as the immunogen for this TLR6 antibody.
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亚型
- Ig Fraction
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anti-Toll-Like Receptor 6 (TLR6) (AA 301-400) antibody
TLR6 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (AA 393-423) antibodyTLR6 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (AA 722-753) antibodyTLR6 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (AA 32-586) antibodyTLR6 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (AA 608-796) antibodyTLR6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (AA 32-200) antibodyTLR6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (N-Term) antibodyTLR6 适用: 人, 小鼠 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (AA 408-424) antibody (PE)TLR6 适用: 人 FACS 宿主: 小鼠 Monoclonal 86B1153-2 PE
anti-Toll-Like Receptor 6 (TLR6) (C-Term) antibodyTLR6 适用: 人, 小鼠 IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 6 (TLR6) (C-Term) antibodyTLR6 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the TLR6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the TLR6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- TLR6 (Toll-Like Receptor 6 (TLR6))
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别名
- TLR6
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背景
- TLR6 participates in the innate immune response to Gram-positive bacteria and fungi. Specifically recognizes diacylated and, to a lesser extent, triacylated lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Cooperates with TLR2 for the cellular activation. In complex with TLR4, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalized and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. [UniProt]
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UniProt
- Q9EPW9
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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