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TLR6 抗体 (AA 393-423)

This anti-TLR6 antibody is a 兔 多克隆 antibody detecting TLR6 in WB, ELISA, IHC 和 FACS. Suitable for 人.
产品编号 ABIN3029174
发货至: 中国

Quick Overview for TLR6 抗体 (AA 393-423) (ABIN3029174)

抗原

See all TLR6 抗体
TLR6 (Toll-Like Receptor 6 (TLR6))

适用

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宿主

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克隆类型

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多克隆

标记

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This TLR6 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

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    AA 393-423

    纯化方法

    Purified

    免疫原

    A portion of amino acids 393-423 from the human protein was used as the immunogen for this TLR6 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the TLR6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Flow Cytometry: 1:10-1:50,Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the TLR6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    TLR6 (Toll-Like Receptor 6 (TLR6))

    别名

    TLR6

    背景

    TLR6, a Type I membrane protein that belongs to the Toll-like rceptor family, participates in the innate immune response to Gram-positive bacteria and fungi. It acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. The protein recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. It binds to TLR2 via their respective extracellular domains, and to MyD88 via their respective TIR domains. TLR6 is detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells.

    UniProt

    Q9Y2C9

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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