TLR4 抗体 (AA 669-698)
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- 抗原 See all TLR4 抗体
- TLR4 (Toll-Like Receptor 4 (TLR4))
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抗原表位
- AA 669-698
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TLR4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), ELISA
- 交叉反应 (详细)
- Expected species reactivity: Bovine, Pig, Hamster
- 纯化方法
- Antigen affinity purified
- 免疫原
- A portion of amino acids 669-698 from the human protein was used as the immunogen for this TLR4 antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product TLR4 Primary Antibody
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- 应用备注
- Titration of the TLR4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the TLR4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- TLR4 (Toll-Like Receptor 4 (TLR4))
- 别名
- TLR4 (TLR4 产品)
- 背景
- TLR4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria.
- UniProt
- O00206
- 途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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