TEK 抗体 (AA 758-789)
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Quick Overview for TEK 抗体 (AA 758-789) (ABIN3029103)
抗原
See all TEK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 758-789
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交叉反应 (详细)
- Expected species reactivity: Bovine
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纯化方法
- Purified
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免疫原
- A portion of amino acids 758-789 from the human protein was used as the immunogen for this TIE2 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the TIE2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the TIE2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
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别名
- TIE2
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背景
- The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
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UniProt
- Q02763
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途径
- RTK signaling, Growth Factor Binding
抗原
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