TFEB 抗体 (AA 271-300)
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北京 101111
Quick Overview for TFEB 抗体 (AA 271-300) (ABIN3029202)
抗原
See all TFEB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 271-300
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交叉反应 （详细）
- Expected species reactivity: Mouse
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 271-300 from the human protein was used as the immunogen for this TFEB antibody.
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亚型
- Ig Fraction
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anti-Transcription Factor EB (TFEB) (AA 1-476) antibody
TFEB 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal S1 unconjugated
anti-Transcription Factor EB (TFEB) (Middle Region) antibodyTFEB 适用: 人, Cow, 犬, 马, 山羊, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) (AA 1-476) antibodyTFEB 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) (AA 1-220) antibodyTFEB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) (N-Term) antibodyTFEB 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) (AA 10-90) antibodyTFEB 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) (N-Term) antibodyTFEB 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) (Internal Region) antibodyVerified TFEB 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Transcription Factor EB (TFEB) (AA 1-476) antibodyTFEB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Titration of the TFEB antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the TFEB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- TFEB (Transcription Factor EB (TFEB))
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别名
- TFEB
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背景
- Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta.
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UniProt
- P19484
抗原
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