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TdT 抗体 (AA 438-467)

This 兔 多克隆 anti-TdT antibody specifically detects TdT in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN3030713
发货至: 中国
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Quick Overview for TdT 抗体 (AA 438-467) (ABIN3030713)

抗原

See all TdT (DNTT) 抗体
TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

适用

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宿主

  • 79
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克隆类型

  • 62
  • 30
  • 1
多克隆

标记

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This TdT antibody is un-conjugated

应用范围

  • 58
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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 438-467

    交叉反应 (详细)

    Expected species reactivity: Mouse

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 438-467 from human DNA nucleotidylexotransferase was used as the immunogen for this TdT antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the TdT antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the TdT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

    别名

    TdT

    背景

    This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

    UniProt

    P04053

    途径

    DNA Damage Repair
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