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TBK1 抗体 (AA 8-35)

The 兔 多克隆 anti-TBK1 antibody is suitable to detect TBK1 in samples from 小鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN3029093
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TBK1 抗体 (AA 8-35) (ABIN3029093)

抗原

See all TBK1 抗体
TBK1 (TANK-Binding Kinase 1 (TBK1))

适用

  • 84
  • 53
  • 35
  • 7
  • 6
  • 6
  • 6
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
小鼠

宿主

  • 91
  • 3
  • 1

克隆类型

  • 70
  • 25
多克隆

标记

  • 57
  • 8
  • 7
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This TBK1 antibody is un-conjugated

应用范围

  • 71
  • 45
  • 44
  • 19
  • 13
  • 9
  • 8
  • 8
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 9
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 8-35

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 8-35 from the mouse protein was used as the immunogen for this Tbk1 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the Tbk1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Tbk1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    TBK1 (TANK-Binding Kinase 1 (TBK1))

    别名

    Tbk1

    背景

    Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response.

    UniProt

    Q9WUN2

    途径

    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
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