tau 抗体 (AA 677-707)
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Quick Overview for tau 抗体 (AA 677-707) (ABIN3031796)
抗原
See all tau 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 677-707
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交叉反应 (详细)
- Expected species reactivity: Mouse, Rat, Bovine
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纯化方法
- Purified
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免疫原
- A portion of amino acids 677-707 from the human protein was used as the immunogen for this TAU antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the TAU antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the TAU antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- tau (tau Protein)
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别名
- tau
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背景
- TAU/MAPT promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. [UniProt]
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UniProt
- P10636
抗原
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