SYVN1 抗体 (AA 586-617)
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北京 101111
Quick Overview for SYVN1 抗体 (AA 586-617) (ABIN3029082)
抗原
See all SYVN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 586-617
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纯化方法
- Purified
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免疫原
- A portion of amino acids 586-617 from the human protein was used as the immunogen for this SYVN1 antibody.
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亚型
- Ig Fraction
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anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 586-617), (C-Term) antibody
SYVN1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB4822 unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (Internal Region) antibodyVerified SYVN1 适用: 人, 大鼠 WB, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 531-617) antibodySYVN1 适用: 人, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (Internal Region) antibodySYVN1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 338-487) antibodySYVN1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (Internal Region) antibodySYVN1 适用: 人, 小鼠, 大鼠, 马, 犬, Cow, 兔, Bat, 猴, Hamster, 非洲爪蟾, 斑马鱼 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 1-617) antibodySYVN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 238-318) antibodySYVN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H4 unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (Internal Region) antibodyVerified SYVN1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 371-420) antibodySYVN1 适用: 人, 小鼠, 大鼠, 马, 犬, 豚鼠, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the SYVN1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:200-1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the SYVN1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))
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别名
- SYVN1 (HRD1)
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背景
- HRD1/SYVN1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress. Expression of SYVN1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum. It is expressed in many tissues, strongly expressed in brain, pancreas, liver, kidney and skeletal muscle. Amano T, et al. reported that Synoviolin/Hrd1 (expressed in rheumatoid synovium) is a novel causative factor for arthropathy by triggering synovial cell outgrowth through its antiapoptotic effects.
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UniProt
- Q86TM6
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途径
- ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
抗原
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