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STIM1 抗体 (AA 509-538)

This 兔 多克隆 anti-STIM1 antibody specifically detects STIM1 in WB, IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN3032757
发货至: 中国
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Quick Overview for STIM1 抗体 (AA 509-538) (ABIN3032757)

抗原

See all STIM1 抗体
STIM1 (Stromal Interaction Molecule 1 (STIM1))

适用

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宿主

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克隆类型

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多克隆

标记

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This STIM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 509-538

    交叉反应 (详细)

    Expected species reactivity: Mouse

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 509-538 from the human protein was used as the immunogen for this STIM1 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the STIM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the STIM1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    STIM1 (Stromal Interaction Molecule 1 (STIM1))

    别名

    STIM1

    背景

    This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene.

    UniProt

    Q13586

    途径

    TCR Signaling, BCR Signaling
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