STIM1 抗体 (AA 509-538)
Our Local Distributor
北京 101111
Quick Overview for STIM1 抗体 (AA 509-538) (ABIN3032757)
抗原
See all STIM1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 509-538
-
交叉反应 (详细)
- Expected species reactivity: Mouse
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 509-538 from the human protein was used as the immunogen for this STIM1 antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the STIM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the STIM1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- STIM1 (Stromal Interaction Molecule 1 (STIM1))
-
别名
- STIM1
-
背景
- This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene.
-
UniProt
- Q13586
-
途径
- TCR Signaling, BCR Signaling
抗原
-