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SP1 抗体

The 小鼠 单克隆 anti-SP1 antibody (Clone 1326CT463-109-176) (ABIN3032703) specifically detects SP1 in WB, ELISA, IF 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN3032703
发货至: 中国
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Quick Overview for SP1 抗体 (ABIN3032703)

抗原

See all SP1 抗体
SP1 (Sp1 Transcription Factor (SP1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This SP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

1326CT463-109-176
  • 纯化方法

    Purified

    免疫原

    This SP1 antibody was produced from a mouse immunized with recombinant Specificity Protein 1.

    亚型

    IgG1 kappa
  • 应用备注

    Titration of the SP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Flow Cytometry: 1:25,Immunofluorescence: 1:25,Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the SP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    SP1 (Sp1 Transcription Factor (SP1))

    别名

    SP1

    背景

    Specificity Protein 1/SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR- alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression. [UniProt]

    UniProt

    P08047

    途径

    Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
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