SOCS7 抗体 (AA 458-486)
Quick Overview for SOCS7 抗体 (AA 458-486) (ABIN3029049)
抗原
See all SOCS7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 458-486
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交叉反应 （详细）
- Expected species reactivity: Mouse
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 458-486 from the human protein was used as the immunogen for this SOCS7 antibody.
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亚型
- Ig Fraction
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anti-Suppressor of Cytokine Signaling 7 (SOCS7) (AA 6-165) antibody
SOCS7 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 7 (SOCS7) (AA 35-84) antibodySOCS7 适用: 人, 小鼠, 大鼠, Cow, 兔, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 7 (SOCS7) (Internal Region) antibodyVerified SOCS7 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 7 (SOCS7) (N-Term) antibodySOCS7 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the SOCS7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the SOCS7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))
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别名
- SOCS7
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背景
- Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
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UniProt
- O14512
抗原
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