SOCS6 抗体 (AA 40-69)
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Quick Overview for SOCS6 抗体 (AA 40-69) (ABIN3029048)
抗原
See all SOCS6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-69
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 40-69 from the human protein was used as the immunogen for this SOCS6 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the SOCS6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the SOCS6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))
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别名
- SOCS6
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背景
- The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.
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UniProt
- O14544
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途径
- JAK/STAT Signaling, Carbohydrate Homeostasis
抗原
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