SMAD4 抗体 (AA 255-284)
Our Local Distributor
北京 101111
Quick Overview for SMAD4 抗体 (AA 255-284) (ABIN3032604)
抗原
See all SMAD4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 255-284
-
交叉反应 (详细)
- Expected species reactivity: Mouse, Rat
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 255-284 from the human protein was used as the immunogen for this SMAD4 antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the SMAD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the SMAD4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- SMAD4 (SMAD Family Member 4 (SMAD4))
-
别名
- SMAD4
-
背景
- SMAD4 is the common SMAD (co-SMAD)mediator of signal transduction by TGF-beta (transforming growth factor). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.
-
UniProt
- Q13485
-
途径
- Cell Division Cycle, Chromatin Binding, Autophagy
抗原
-