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SKP2 抗体 (AA 156-185)

This anti-SKP2 antibody is a 兔 多克隆 antibody detecting SKP2 in WB, ELISA 和 FACS. Suitable for 人.
产品编号 ABIN3032602
发货至: 中国

Quick Overview for SKP2 抗体 (AA 156-185) (ABIN3032602)

抗原

See all SKP2 抗体
SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))

适用

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宿主

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克隆类型

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多克隆

标记

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This SKP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 156-185

    纯化方法

    Purified

    免疫原

    A portion of amino acids 156-185 from the human protein was used as the immunogen for this SKP2 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the SKP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the SKP2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))

    别名

    SKP2

    背景

    SKP2 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class, in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas.

    UniProt

    Q13309

    途径

    Mitotic G1-G1/S Phases
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