RAD51C 抗体 (AA 169-198)
Our Local Distributor
北京 101111
Quick Overview for RAD51C 抗体 (AA 169-198) (ABIN3032429)
抗原
See all RAD51C 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 169-198
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 169-198 from the human protein was used as the immunogen for this RAD51C antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the RAD51C antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the RAD51C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))
-
别名
- RAD51C
-
背景
- This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.
-
UniProt
- O43502
-
途径
- DNA Damage Repair
抗原
-