PKM2 抗体 (AA 121-151)
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Quick Overview for PKM2 抗体 (AA 121-151) (ABIN3032418)
抗原
See all PKM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 121-151
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交叉反应 (详细)
- Expected species reactivity: Rabbit, Rat
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纯化方法
- Purified
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免疫原
- A portion of amino acids 121-151 from the human protein was used as the immunogen for this Pyruvate Kinase antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Pyruvate Kinase antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Pyruvate Kinase antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PKM2 (Pyruvate Kinase M2 (PKM2))
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别名
- Pyruvate Kinase (PKM2)
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背景
- PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
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UniProt
- P14618
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途径
- Warburg Effect
抗原
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