PROX1 抗体 (AA 492-520)
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Quick Overview for PROX1 抗体 (AA 492-520) (ABIN3032345)
抗原
See all PROX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 492-520
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 492-520 from the human protein was used as the immunogen for this PROX1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the PROX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the PROX1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PROX1 (Prospero Homeobox 1 (PROX1))
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别名
- PROX1
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背景
- Prospero homeobox protein 1 is a transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3. [UniProt]
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UniProt
- Q92786
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途径
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation
抗原
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