PRMT5 抗体 (AA 76-104)
Quick Overview for PRMT5 抗体 (AA 76-104) (ABIN3032360)
抗原
See all PRMT5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 76-104
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交叉反应 （详细）
- Expected species reactivity: Bovine, Primate
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 76-104 from the human protein was used as the immunogen for this PRMT5 antibody.
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亚型
- Ig Fraction
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anti-Protein Arginine Methyltransferase 5 (PRMT5) (AA 40-140) antibody
PRMT5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (Internal Region) antibodyPRMT5 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (AA 21-70) antibodyPRMT5 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, 猴, 豚鼠, Pig, 斑马鱼, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (N-Term) antibodyPRMT5 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (AA 297-534) antibodyPRMT5 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) antibodyPRMT5 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 2H4 unconjugated Recombinant Antibody
anti-Protein Arginine Methyltransferase 5 (PRMT5) antibodyPRMT5 适用: 人, 小鼠 WB, IHC, IF, IP, ChIP, IC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (N-Term) antibodyPRMT5 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (AA 591-621) antibodyPRMT5 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) antibodyPRMT5 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the PRMT5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the PRMT5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))
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别名
- PRMT5
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背景
- Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono-and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. May regulate the SUPT5H transcriptional elongation properties. May be part of a pathway that is connected to a chloride current, possibly through cytoskeletal rearrangement. Methylates histone H2A and H4 'Arg-3' during germ cell development. Methylates histone H3 'Arg-8', which may repress transcription. Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. Methylates RPS10.
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UniProt
- O14744
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途径
- Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development
抗原
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