PKM2 抗体 (AA 116-145)
Our Local Distributor
北京 101111
Quick Overview for PKM2 抗体 (AA 116-145) (ABIN3032239)
抗原
See all PKM2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 116-145
-
交叉反应 (详细)
- Expected species reactivity: Mouse, Rabbit, Rat
-
纯化方法
- Purified
-
免疫原
- A portion of amino acids 116-145 from the human protein was used as the immunogen for this PKM2 antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the PKM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the PKM2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- PKM2 (Pyruvate Kinase M2 (PKM2))
-
别名
- PKM2
-
背景
- PKM2 encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
-
UniProt
- P14618
-
途径
- Warburg Effect
抗原
-