PKM2 抗体 (AA 476-505)
Quick Overview for PKM2 抗体 (AA 476-505) (ABIN3032237)
抗原
See all PKM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 476-505
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纯化方法
- Purified
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免疫原
- A portion of amino acids 476-505 from the human protein was used as the immunogen for this PKM2 antibody.
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亚型
- Ig Fraction
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anti-Pyruvate Kinase M2 (PKM2) (AA 294-470) antibody
PKM2 适用: 人 WB, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 141-248) antibodyPKM2 适用: 人 WB, IHC, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (pTyr105) antibodyPKM2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 476-505), (C-Term) antibodyPKM2 适用: 人, 小鼠, 大鼠, 猴 WB, IHC (p), IF 宿主: 兔 Polyclonal RB3697 unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 383-417), (C-Term) antibodyPKM2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18405 unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 116-145) antibodyPKM2 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 255-350) antibodyPKM2 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IHC (p), ICC, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 1-531) antibodyPKM2 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 51-150) antibodyPKM2 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IHC (p), ICC, IF (p), IF (cc), IHC (fro) 宿主: 小鼠 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 1-531) antibodyPKM2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Titration of the PKM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:200,Western blot: 1:1000,IHC (Paraffin): 1:50-1:1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the PKM2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PKM2 (Pyruvate Kinase M2 (PKM2))
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别名
- PKM2
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背景
- PKM2 is a glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival. [UniProt]
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UniProt
- P14618
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途径
- Warburg Effect
抗原
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