PRKD3 抗体 (AA 352-384)
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Quick Overview for PRKD3 抗体 (AA 352-384) (ABIN3032380)
抗原
See all PRKD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 352-384
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纯化方法
- Purified
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免疫原
- A portion of amino acids 352-384 from the human protein was used as the immunogen for this PKC nu antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the PKC nu antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,IF: 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the PKC nu antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PRKD3 (Protein Kinase D3 (PRKD3))
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别名
- PKC nu
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背景
- Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC nu is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.
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UniProt
- O94806
抗原
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