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PITX2 抗体 (AA 122-151)

This anti-PITX2 antibody is a 兔 多克隆 antibody detecting PITX2 in WB, ELISA 和 IF. Suitable for 人.
产品编号 ABIN3032141
发货至: 中国

Quick Overview for PITX2 抗体 (AA 122-151) (ABIN3032141)

抗原

See all PITX2 抗体
PITX2 (Paired-Like Homeodomain 2 (PITX2))

适用

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宿主

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克隆类型

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多克隆

标记

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This PITX2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 122-151

    交叉反应 (详细)

    Expected species reactivity: Mouse, Rat, Chicken, Zebrafish, Xenopus

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 122-151 from the human protein was used as the immunogen for this PITX2 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the PITX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the PITX2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    PITX2 (Paired-Like Homeodomain 2 (PITX2))

    别名

    PITX2

    背景

    Pilx2 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. It plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this protein are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development.

    UniProt

    Q99697

    途径

    Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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