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TSC1 抗体 (pThr416)

This anti-TSC1 antibody is a 兔 多克隆 antibody detecting TSC1 in DB 和 ELISA. Suitable for 小鼠.
产品编号 ABIN3029301
发货至: 中国

Quick Overview for TSC1 抗体 (pThr416) (ABIN3029301)

抗原

See all TSC1 抗体
TSC1 (Tuberous Sclerosis 1 (TSC1))

适用

  • 191
  • 137
  • 52
  • 24
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  • 2
  • 1
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小鼠

宿主

  • 304
  • 16
  • 1
  • 1

克隆类型

  • 305
  • 17
多克隆

标记

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This TSC1 antibody is un-conjugated

应用范围

  • 230
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  • 95
  • 32
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Dot Blot (DB), ELISA
  • 抗原表位

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    pThr416

    纯化方法

    Antigen affinity purified

    免疫原

    This phospho-TSC1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT416 of mouse TSC1.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the phospho-TSC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the phospho-TSC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    TSC1 (Tuberous Sclerosis 1 (TSC1))

    别名

    TSC1

    背景

    In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).

    UniProt

    Q9EP53

    途径

    RTK signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation
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