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SMAD4 抗体 (pThr277)

This anti-SMAD4 antibody is a 兔 多克隆 antibody detecting SMAD4 in ELISA, IHC, IF 和 DB. Suitable for 人.
产品编号 ABIN3032606
发货至: 中国

Quick Overview for SMAD4 抗体 (pThr277) (ABIN3032606)

抗原

See all SMAD4 抗体
SMAD4 (SMAD Family Member 4 (SMAD4))

适用

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宿主

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克隆类型

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多克隆

标记

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This SMAD4 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Dot Blot (DB)
  • 抗原表位

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    pThr277

    交叉反应 (详细)

    Expected species reactivity: Mouse, Rat

    纯化方法

    Antigen affinity purified

    免疫原

    This phospho-SMAD4 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT277 of human SMAD4.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the phospho-SMAD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Dot blot: 1:500,IHC (Paraffin): 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the phospho-SMAD4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    SMAD4 (SMAD Family Member 4 (SMAD4))

    别名

    SMAD4

    背景

    Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.

    UniProt

    Q13485

    途径

    Cell Division Cycle, Chromatin Binding, Autophagy
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