OCT4 抗体 (pSer236)
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Quick Overview for OCT4 抗体 (pSer236) (ABIN3032291)
抗原
See all OCT4 (POU5F1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer236
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交叉反应 (详细)
- Expected species reactivity: Mouse, Bovine, Pig
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纯化方法
- Antigen affinity purified
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免疫原
- This phospho-Oct4 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS236 of human OCT4.
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亚型
- Ig Fraction
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应用备注
- Titration of the phospho-Oct4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the phospho-Oct4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
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别名
- Oct4
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背景
- OCT4 encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6,22)(p21,q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
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UniProt
- Q01860
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途径
- Stem Cell Maintenance
抗原
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