LC3C 抗体 (pSer12)
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北京 101111
Quick Overview for LC3C 抗体 (pSer12) (ABIN3031792)
抗原
See all LC3C (MAP1LC3C) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer12
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交叉反应 （详细）
- Expected species reactivity: Bovine, Mouse, Rat
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纯化方法
- Antigen affinity purified
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免疫原
- This phospho-LC3C antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS12 of human LC3C.
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亚型
- Ig Fraction
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anti-Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C) (pSer12) antibody
MAP1LC3C 适用: 人 WB, DB 宿主: 兔 Polyclonal RB10838-RB16769 unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C) (AA 1-30) antibodyMAP1LC3C 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C) (Thr48) antibodyMAP1LC3C 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C) (AA 1-147) antibodyMAP1LC3C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C) (pSer12) antibodyMAP1LC3C 适用: 人 WB, DB 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C) (AA 1-147) antibodyMAP1LC3C 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C) (AA 1-30), (N-Term) antibodyMAP1LC3C 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the phospho-LC3C antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Dot blot: 1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the phospho-LC3C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- LC3C (MAP1LC3C) (Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C))
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别名
- LC3C
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背景
- MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. These proteins are involved in formation of autophagosomal vacuoles (autophagosomes). MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. MAP1LC3a is one of the light chain subunits and can associate with either MAP1A or MAP1B. The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole).
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UniProt
- Q9H492
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途径
- Autophagy
抗原
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