KIT 抗体 (pThr274)
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Quick Overview for KIT 抗体 (pThr274) (ABIN3031692)
抗原
See all KIT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr274
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纯化方法
- Antigen affinity purified
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免疫原
- This phospho-c-Kit antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT274 of human c-Kit.
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亚型
- Ig Fraction
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应用备注
- Titration of the phospho-c-Kit antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the phospho-c-Kit antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
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别名
- C-Kit
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背景
- This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P10721
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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