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c-FOS 抗体 (pThr232)

This anti-c-FOS antibody is a 兔 多克隆 antibody detecting c-FOS in ELISA 和 DB. Suitable for 人.
产品编号 ABIN3030222
发货至: 中国

Quick Overview for c-FOS 抗体 (pThr232) (ABIN3030222)

抗原

See all c-FOS (c-Fos) 抗体
c-FOS (c-Fos) (c-Fos)

适用

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宿主

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克隆类型

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多克隆

标记

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This c-FOS antibody is un-conjugated

应用范围

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ELISA, Dot Blot (DB)
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    pThr232

    纯化方法

    Antigen affinity purified

    免疫原

    This phospho-c-Fos antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT232 of the human protein.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the phospho-c-Fos antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the phospho-c-Fos antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    c-FOS (c-Fos) (c-Fos)

    别名

    C-Fos

    背景

    C-Fos is a nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum. [UniProt]

    UniProt

    P01100

    途径

    S100 Proteins
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