PDGFRA 抗体 (AA 698-727)
Our Local Distributor
北京 101111
Quick Overview for PDGFRA 抗体 (AA 698-727) (ABIN3032255)
抗原
See all PDGFRA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 698-727
-
交叉反应 (详细)
- Expected species reactivity: Chicken, Mouse, Rat, Xenopus
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 698-727 from the human alpha protein was used as the immunogen for this PDGFR antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the PDGFR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the PDGFR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
-
背景
- As a receptor for PDGFA, PDGFR alpha promotes or inhibits cell proliferation and cell migration. Binding of its cognate ligands - homodimeric PDGFA, homodimeric PDGFB, heterodimers formed by PDGFA and PDGFB or homodimeric PDGFC -leads to the activation of several signaling cascades, the response depends on the nature of the bound ligand and is modulated by the formation of heterodimers between PDGFRA and PDGFRB. [UniProt]
-
UniProt
- P16234
-
途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
抗原
-