PDGFRA 抗体 (AA 740-769)
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Quick Overview for PDGFRA 抗体 (AA 740-769) (ABIN3032251)
抗原
See all PDGFRA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 740-769
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交叉反应 (详细)
- Expected species reactivity: Mouse, Rat, Xenopus
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 740-769 from the human protein was used as the immunogen for this PDGFR alpha antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the PDGFR alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the PDGFR alpha antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
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别名
- PDGFR alpha
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背景
- PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
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UniProt
- P16234
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
抗原
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