This NOTCH4 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1819-1851 amino acids from the C-terminal region of human NOTCH4.
Titration of the NOTCH4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000
限制
仅限研究用
状态
Liquid
缓冲液
In 1X PBS, pH 7.4, with 0.09 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot the NOTCH4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
抗原
NOTCH4
(Notch 4 (NOTCH4))
别名
NOTCH4
背景
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity).