NOTCH4 抗体 (C-Term)
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Quick Overview for NOTCH4 抗体 (C-Term) (ABIN3032033)
抗原
See all NOTCH4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Antigen affinity purified
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免疫原
- This NOTCH4 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1819-1851 amino acids from the C-terminal region of human NOTCH4.
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亚型
- Ig Fraction
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应用备注
- Titration of the NOTCH4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the NOTCH4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- NOTCH4 (Notch 4 (NOTCH4))
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别名
- NOTCH4
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背景
- Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity).
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UniProt
- Q99466
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途径
- Notch Signaling
抗原
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