NKX3-1 抗体 (AA 3-1)
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北京 101111
Quick Overview for NKX3-1 抗体 (AA 3-1) (ABIN3032012)
抗原
See all NKX3-1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3-1
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 3-1 from the mouse protein was used as the immunogen for this Nkx3.1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Nkx3.1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Nkx3.1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- NKX3-1 (NK3 Homeobox 1 (NKX3-1))
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别名
- Nkx3.1
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背景
- Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor (By similarity). Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells. Play a role in the formation of minor salivary glands (particularly palatine and lingual glands). Essential for appropriate differentiation and secretory function of the bulbourethral gland.
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UniProt
- P97436
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus
抗原
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