MAP3K14 抗体 (AA 119-148)
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Quick Overview for MAP3K14 抗体 (AA 119-148) (ABIN3031848)
抗原
See all MAP3K14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 119-148
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纯化方法
- Purified
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免疫原
- A portion of amino acids 119-148 from the human protein was used as the immunogen for this NIK antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the NIK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the NIK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))
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别名
- NIK (NF-kappa-beta-Inducing Kinase)
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背景
- NIK (MAP3K14), a member of the Ser/Thr protein kinase family, binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
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UniProt
- Q99558
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途径
- NF-kappaB Signaling, TCR Signaling
抗原
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