NEUROD1 抗体 (AA 15-45)
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北京 101111
Quick Overview for NEUROD1 抗体 (AA 15-45) (ABIN3031977)
抗原
See all NEUROD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 15-45
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纯化方法
- Purified
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免疫原
- A portion of amino acids 15-45 from the human protein was used as the immunogen for this NeuroD1 antibody.
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亚型
- Ig Fraction
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anti-Neuronal Differentiation 1 (NEUROD1) (AA 26-91) antibody
NEUROD1 适用: 人 ELISA, FACS, IHC 宿主: 小鼠 Monoclonal 4G12B4 unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 201-300) antibodyNEUROD1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3H8 unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 26-91) antibodyNEUROD1 适用: 人, 小鼠, 猴 ELISA 宿主: 小鼠 Monoclonal 6E9G12 unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (N-Term) antibodyNEUROD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 15-45) antibodyNEUROD1 适用: 人 WB, IF, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 15-45), (N-Term) antibodyNEUROD1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB02901 unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 26-91) antibodyNEUROD1 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 21-120) antibodyNEUROD1 适用: 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 1-70) antibodyNEUROD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Differentiation 1 (NEUROD1) (AA 154-356) antibodyNEUROD1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the NeuroD1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the NeuroD1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- NEUROD1 (Neuronal Differentiation 1 (NEUROD1))
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别名
- NeuroD1
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背景
- NeuroD1 acts as a differentiation factor during neurogenesis. They are expressed transiently in a subset of neurons in the central and peripheral nervous systems at the time of their terminal differentiation. NeuroD1 is a basic helix-loop-helix (bHLH) protein contain 1 bHLH domain. NeuroD1 is a transcriptional activator, for efficient DNA binding it requires dimerization with another bHLH protein. It was reported that NeuroD1 involves heterodimerization with the ubiquitous bHLH protein E47, and regulates insulin gene expression by binding to a critical E-box motif on the insulin promoter. Defects in NEUROD1 causes maturity onset diabetes of the young type VI. MODY6 is a form of non-insulin-dependent diabetes mellitus (NIDDM) characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.
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UniProt
- Q13562
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途径
- Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis
抗原
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