NEUROD1 抗体 (AA 318-348)
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Quick Overview for NEUROD1 抗体 (AA 318-348) (ABIN3031978)
抗原
See all NEUROD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 318-348
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纯化方法
- Purified
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免疫原
- A portion of amino acids 318-348 from the human protein was used as the immunogen for this NeuroD1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the NeuroD1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the NeuroD1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- NEUROD1 (Neuronal Differentiation 1 (NEUROD1))
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别名
- NeuroD1
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背景
- NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to bind to the insulin gene E-box. Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6). MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.
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UniProt
- Q13562
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途径
- Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis
抗原
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