MME 抗体 (AA 506-534)
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Quick Overview for MME 抗体 (AA 506-534) (ABIN3031746)
抗原
See all MME 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 506-534
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交叉反应 （详细）
- Expected species reactivity: Mouse, Rat, Rabbit
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 506-534 from the human protein was used as the immunogen for this Neprilysin antibody.
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亚型
- Ig Fraction
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anti-Membrane Metallo-Endopeptidase (MME) (AA 52-352) antibody
MME 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 52-246) antibodyMME 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 7D4B1 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 501-600) antibodyMME 适用: 人, 大鼠, 小鼠 WB, FACS, ELISA, ICC, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 382-538) antibodyMME 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibodyMME 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal MME-1870 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 286-428) antibodyMME 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibodyMME 适用: 人 WB, IHC, ELISA, StM, Coat 宿主: 小鼠 Monoclonal MME-1892 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) antibody (FITC)MME 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-78 FITC
anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibodyMME 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 3G6B11 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibodyMME 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 6G12E12 unconjugated
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应用备注
- Titration of the Neprilysin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Neprilysin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MME (Membrane Metallo-Endopeptidase (MME))
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别名
- Neprilysin
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物质类
- Chemical
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背景
- MME is a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a oprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.
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UniProt
- P08473
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途径
- RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
抗原
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